Pfizer
Senior Associate Scientist, Oncology Central Cell Bank
United States - California - San Diego · Posted 1h ago
Job Description
POSITION SUMMARY
As a member of our In Vivo Pharmacology team, you will play a key role supporting the Oncology Central Cell Bank in our Oncology Research Unit.
In this laboratory-based role, you will primarily manage the procurement, collection, expansion, storage, and distribution of all cell lines to serve the diverse needs of research and development activities. You will act as a technical expert in sterile cell culture techniques, particularly with transformed or immortalized mouse and human cancer cell lines. You will work closely with colleagues from various research groups, managing both routine workflows and complex troubleshooting to maintain a world-class cell repository.
POSITION RESPONSIBILITIES
Cell Line Management: Direct the procurement, onboarding, expansion, storage (cryopreservation), and distribution of all mammalian cell lines to support downstream oncology and immuno-oncology studies.
Mammalian Cell Culture Maintenance: Cultivate and maintain both existing cell lines and newly onboarded lines, focusing heavily on sterile cell culture techniques for transformed/immortalized human and murine cell lines.
Quality Control & Inventory: Execute regular, rigorous QC processes to ensure highly accurate cell inventory tracking, contamination-free cultures, and efficient completion of all Central Cell Bank distribution requests.
Audit & Regulatory Readiness: Maintain precise, timely, and complete documentation and records in electronic laboratory notebooks (ELNs) to support compliance audits and IND filing purposes.
Vendor & CRO Coordination: Manage weekly communications and updates with the hiring manager and contract research organizations (CROs) to ensure set milestones are met, goals are achieved, and reagents are secured.
MINIMUM QUALIFICATIONS
Bachelor of Science (BS) degree in Biology, Immunology, Oncology, Molecular Biology, or a closely related scientific discipline.
3+ years of relevant hands-on laboratory experience
Current knowledge of oncology, immunology, and immuno-oncology research and/or drug discovery and development
Exceptional hands-on experience with sterile cell culture techniques, specifically handling transformed and immortalized human and murine cell lines (both adherent and suspension)
High proficiency with standard scientific and office software (e.g., Excel, Word, PowerPoint, data analysis tools)
Experience prioritizing work to meet tight deadlines, and managing multiple requests simultaneously
Excellent written, oral, and presentation skills with experience providing clear weekly updates to management and key stakeholders
Experience in a fast-paced and highly collaborative team environment
PREFERRED QUALIFICATIONS
Experience working within a centralized cell repository, cell banking core, or high-throughput cell processing facility.
Experience troubleshooting challenging cell culture properties (e.g., optimizing post-thaw viability, handling clumpy suspension cell lines, and executing standardized dissociation protocols).
Familiarity with automated cell counters, liquid handling systems, or automated incubation platforms.
PHYSICAL/MENTAL REQUIREMENTS
Lifting of up to 30 pounds, frequent standing, walking, bending, and sitting at biosafety cabinets or lab benches.
Performing repetitive pipetting and manual tasks requiring fine motor skills.
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Must be willing and able to work after hours (including occasional weekends) as needed to maintain culture lines and ensure overall study integrity.
Work Location Assignment: On Premise
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
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